Effect of eflornithine on mutation frequency in temozolomide-treated U87MG cells

Treatment of infiltrative glioma presents a number of unique challenges due to poor penetration of typical chemotherapeutic agents into the infiltrating edge of tumors. The current chemotherapy options include nitrosoureas (e.g., lomustine) and the imidazotetrazine-class monofunctional DNA alkylatin...

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Detalles Bibliográficos
Autores principales: Yam, Noymi, Levin, Jason, Bao, Zhengzheng, Qian, Wubin, Levin, Victor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646829/
https://www.ncbi.nlm.nih.gov/pubmed/33216820
http://dx.doi.org/10.18632/oncotarget.27782

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