Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells

IGF2 is essential in breast differentiation, lactation, tumor growth, and in breast cancer (BC) development and progression. This growth factor also inhibits apoptosis and promotes metastasis and chemoresistance, contributing to more aggressive tumors. We previously demonstrated that IGF2 protein le...

Descripción completa

Detalles Bibliográficos
Autores principales: Radhakrishnan, Vinodh Kumar, Ravichandran, Kameswaran, Eke, Chibuzo, Ortiz-Vicil, Amanda, Tan, Qianwei, León, Marino De, León, Daisy D. De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646830/
https://www.ncbi.nlm.nih.gov/pubmed/33216823
http://dx.doi.org/10.18632/oncotarget.27655

Ejemplares similares

Ejemplares similares