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Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model

Conventional cancer chemotherapies are not fully efficacious and do not target tumors, leading to significant treatment-related morbidities. A number of genetically attenuated cancer-targeting bacteria are being developed to safely target tumors in vivo. Here we report the toxicological, tumor-targe...

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Detalles Bibliográficos
Autores principales: Kazmierczak, Robert A., Dhagat-Mehta, Bakul, Gulden, Elke, Lee, Li, Ma, Lixin, Davis-Stober, Clintin P., Barnett, Austen A., Chabu, Yves C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646835/
https://www.ncbi.nlm.nih.gov/pubmed/33216833
http://dx.doi.org/10.18632/oncotarget.27769