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Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress

Hypertrophic scars (HSs) are a progressive fibroproliferation disorder caused by abnormal tissue repair after deep skin injury, and are characterized by continuous activation of fibroblasts and excessive deposition of extracellular matrix. Arctigenin (ATG), a phytomedicine derived from certain plant...

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Detalles Bibliográficos
Autores principales: Jiang, Ling, Deng, Ying, Li, Wei, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646887/
https://www.ncbi.nlm.nih.gov/pubmed/33174021
http://dx.doi.org/10.3892/mmr.2020.11539