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Cathepsin B aggravated doxorubicin-induced myocardial injury via NF-κB signalling

Myocyte apoptosis and oxidative stress key critical roles in the process of doxorubicin (DOX)-induced cardiotoxicity. However, how apoptosis and oxidative stress arise in DOX-induced heart injury remains largely unknown. Cathepsin B (CTSB) is a typical lysosomal cysteine protease that is associated...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Cai, Zhulan, Hu, Tongtong, Yao, Qi, Zhang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646931/
https://www.ncbi.nlm.nih.gov/pubmed/33173960
http://dx.doi.org/10.3892/mmr.2020.11583

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