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Identifying the mechanisms underlying the protective effect of tetramethylpyrazine against cisplatin-induced in vitro ototoxicity in HEI-OC1 auditory cells using gene expression profiling

Sensorineural hearing loss is prevalent in patients receiving cisplatin therapy. Tetramethylpyrazine (Tet) and tanshinone IIA (Tan IIA) have protective roles against hearing impairment or ototoxicity. The present study aimed to investigate the molecular mechanisms underlying cisplatin-induced ototox...

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Detalles Bibliográficos
Autores principales: Guan, Guofang, He, Xiao, Chen, Jingjing, Bin, Li, Tang, Xuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646960/
https://www.ncbi.nlm.nih.gov/pubmed/33174043
http://dx.doi.org/10.3892/mmr.2020.11631

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