Cargando…

Upregulated lnc-HRK-2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration

Intervertebral disc (IVD) degeneration is a complicated physiological change involving cellular senescence, inflammation and the degradation of the extracellular matrix. Long non-coding RNAs (lncRNAs) have been identified as new players in IVD degeneration. The present study aimed to identify lncRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Dongbo, Hong, Dinggang, Tang, Fuyu, Wang, Yuan, Li, Jianfeng, Li, Linqing, Chen, Huaming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646984/ https://www.ncbi.nlm.nih.gov/pubmed/33174041 http://dx.doi.org/10.3892/mmr.2020.11603

Ejemplares similares

Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008)

PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022)

The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration
por: Liu, Chang, et al.
Publicado: (2021)

TMT-Based Proteomics Analysis of Senescent Nucleus Pulposus from Patients with Intervertebral Disc Degeneration
por: Zhang, Guangzhi, et al.
Publicado: (2023)

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
por: Sakai, Daisuke, et al.
Publicado: (2012)

Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration
por: Li, Zheng, et al.
Publicado: (2019)

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats
por: Wang, Jianle, et al.
Publicado: (2018)

ERBB2-PTGS2 axis promotes intervertebral disc degeneration by regulating senescence of nucleus pulposus cells
por: Li, Zhao-Cheng., et al.
Publicado: (2023)

Psoralen synergizes with exosome-loaded SPC25 to alleviate senescence of nucleus pulposus cells in intervertebral disc degeneration
por: Yang, Lei, et al.
Publicado: (2023)

Natural Products of Pharmacology and Mechanisms in Nucleus Pulposus Cells and Intervertebral Disc Degeneration
por: Chen, Hai-Wei, et al.
Publicado: (2021)

Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration
por: Liu, Fan-jie, et al.
Publicado: (2021)

Effects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells
por: Tang, Hengtao, et al.
Publicado: (2022)

Rescuing Nucleus Pulposus Cells From Senescence via Dual‐Functional Greigite Nanozyme to Alleviate Intervertebral Disc Degeneration
por: Shi, Yu, et al.
Publicado: (2023)

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration
por: Jia, Haoruo, et al.
Publicado: (2022)

Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration
por: Gao, Bo, et al.
Publicado: (2022)

Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
por: Rajasekaran, Shanmuganathan, et al.
Publicado: (2020)

Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration
por: Chen, Jian, et al.
Publicado: (2018)

Ex Vivo Observation of Human Nucleus Pulposus Chondrocytes Isolated From Degenerated Intervertebral Discs
por: Wang, Feng, et al.
Publicado: (2011)

The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc
por: Phillips, Kate L E, et al.
Publicado: (2013)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs
por: Feng, Xu, et al.
Publicado: (2018)

Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells
por: Xie, Chenglong, et al.
Publicado: (2022)

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration
por: Zhang, Guang‐Zhi, et al.
Publicado: (2021)

ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration
por: Ding, Jingyu, et al.
Publicado: (2021)

Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway
por: Zhou, Chengcong, et al.
Publicado: (2022)

Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration in vivo
por: Liu, Huiyong, et al.
Publicado: (2018)

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
por: Wang, Weiheng, et al.
Publicado: (2018)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2018)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2019)

Effects of the NF-κB/p53 signaling pathway on intervertebral disc nucleus pulposus degeneration
por: Zhang, Litao, et al.
Publicado: (2020)

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo
por: Wang, Hao, et al.
Publicado: (2020)

Mechanism of Long Noncoding RNA HOTAIR in Nucleus Pulposus Cell Autophagy and Apoptosis in Intervertebral Disc Degeneration
por: Zhang, Shujun, et al.
Publicado: (2022)

Single-Cell RNA Sequencing of the Nucleus Pulposus Reveals Chondrocyte Differentiation and Regulation in Intervertebral Disc Degeneration
por: Han, Shuo, et al.
Publicado: (2022)

Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis
por: Zhang, Xiao-Bo, et al.
Publicado: (2022)

Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling
por: Fan, Hong, et al.
Publicado: (2022)

DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status
por: Dong, Xiwen, et al.
Publicado: (2022)

Expression of GADD45G and CAPRIN1 in Human Nucleus Pulposus: Implications for Intervertebral Disc Degeneration
por: Kawaguchi, Koki, et al.
Publicado: (2023)

CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3β Pathway
por: Du, Jiacheng, et al.
Publicado: (2022)

BRD4 Inhibition Suppresses Senescence and Apoptosis of Nucleus Pulposus Cells by Inducing Autophagy during Intervertebral Disc Degeneration: An In Vitro and In Vivo Study
por: Zhang, Guang-Zhi, et al.
Publicado: (2022)

Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NF-κB signaling pathway
por: Yang, Huan, et al.
Publicado: (2022)

Changes in the Molecular Phenotype of Nucleus Pulposus Cells with Intervertebral Disc Aging
por: Tang, Xinyan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2h9k081p3p590s96qborhnst4s