Weight loss, insulin resistance, and study design confound results in a meta-analysis of animal models of fatty liver

The classical drug development pipeline necessitates studies using animal models of human disease to gauge future efficacy in humans, however there is a low conversion rate from success in animals to humans. Non-alcoholic fatty liver disease (NAFLD) is a complex chronic disease without any establish...

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Detalles Bibliográficos
Autores principales: Hunter, Harriet, de Gracia Hahn, Dana, Duret, Amedine, Im, Yu Ri, Cheah, Qinrong, Dong, Jiawen, Fairey, Madison, Hjalmarsson, Clarissa, Li, Alice, Lim, Hong Kai, McKeown, Lorcan, Mitrofan, Claudia-Gabriela, Rao, Raunak, Utukuri, Mrudula, Rowe, Ian A, Mann, Jake P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647398/
https://www.ncbi.nlm.nih.gov/pubmed/33063664
http://dx.doi.org/10.7554/eLife.56573

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