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Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China

Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were st...

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Autores principales: Jie, Li Shao, Yu, Yuan, Ping, Zeng Jian, Dong, Xiang Xu, Ping, Chai Xiang, Chao, Hu, Li, Yang, Jing, Yang, Ling, Tan Yan, Yan, Jiang Ming, Peng, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647591/
https://www.ncbi.nlm.nih.gov/pubmed/33157941
http://dx.doi.org/10.1097/MD.0000000000022980
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author Jie, Li Shao
Yu, Yuan
Ping, Zeng Jian
Dong, Xiang Xu
Ping, Chai Xiang
Chao, Hu
Li, Yang
Jing, Yang
Ling, Tan Yan
Yan, Jiang Ming
Peng, Ling
author_facet Jie, Li Shao
Yu, Yuan
Ping, Zeng Jian
Dong, Xiang Xu
Ping, Chai Xiang
Chao, Hu
Li, Yang
Jing, Yang
Ling, Tan Yan
Yan, Jiang Ming
Peng, Ling
author_sort Jie, Li Shao
collection PubMed
description Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were studied, and those whose conditions changed after admission were compared. Their clinical characteristics and experimental indicators were compared using SPSS software and R language to build a disease risk prediction model. Patients with condition changes after admission were older and had more blood cell abnormalities and impaired organ function (decreased albumin, elevated D-dimer) than normal patients. We found that age, neutrophil ratio, D-dimer, chest Computed tomograpgy (CT) changes, and glucocorticoid use were risk factors for COVID-19 pneumonia after admission. Elderly patients are more susceptible to disease changes after COVID-19 pneumonia; COVID-19 pneumonia patients who develop disease changes after admission have higher neutrophil ratios, increased D-dimer levels, chest imaging changes, and glucocorticoid usage. Additional research is needed.
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spelling pubmed-76475912020-11-09 Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China Jie, Li Shao Yu, Yuan Ping, Zeng Jian Dong, Xiang Xu Ping, Chai Xiang Chao, Hu Li, Yang Jing, Yang Ling, Tan Yan Yan, Jiang Ming Peng, Ling Medicine (Baltimore) 4900 Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were studied, and those whose conditions changed after admission were compared. Their clinical characteristics and experimental indicators were compared using SPSS software and R language to build a disease risk prediction model. Patients with condition changes after admission were older and had more blood cell abnormalities and impaired organ function (decreased albumin, elevated D-dimer) than normal patients. We found that age, neutrophil ratio, D-dimer, chest Computed tomograpgy (CT) changes, and glucocorticoid use were risk factors for COVID-19 pneumonia after admission. Elderly patients are more susceptible to disease changes after COVID-19 pneumonia; COVID-19 pneumonia patients who develop disease changes after admission have higher neutrophil ratios, increased D-dimer levels, chest imaging changes, and glucocorticoid usage. Additional research is needed. Lippincott Williams & Wilkins 2020-11-06 /pmc/articles/PMC7647591/ /pubmed/33157941 http://dx.doi.org/10.1097/MD.0000000000022980 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle 4900
Jie, Li Shao
Yu, Yuan
Ping, Zeng Jian
Dong, Xiang Xu
Ping, Chai Xiang
Chao, Hu
Li, Yang
Jing, Yang
Ling, Tan Yan
Yan, Jiang Ming
Peng, Ling
Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title_full Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title_fullStr Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title_full_unstemmed Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title_short Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
title_sort risk factors for coronavirus disease 2019 pneumonia after admission outside wuhan, china
topic 4900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647591/
https://www.ncbi.nlm.nih.gov/pubmed/33157941
http://dx.doi.org/10.1097/MD.0000000000022980
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