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Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were st...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647591/ https://www.ncbi.nlm.nih.gov/pubmed/33157941 http://dx.doi.org/10.1097/MD.0000000000022980 |
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author | Jie, Li Shao Yu, Yuan Ping, Zeng Jian Dong, Xiang Xu Ping, Chai Xiang Chao, Hu Li, Yang Jing, Yang Ling, Tan Yan Yan, Jiang Ming Peng, Ling |
author_facet | Jie, Li Shao Yu, Yuan Ping, Zeng Jian Dong, Xiang Xu Ping, Chai Xiang Chao, Hu Li, Yang Jing, Yang Ling, Tan Yan Yan, Jiang Ming Peng, Ling |
author_sort | Jie, Li Shao |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were studied, and those whose conditions changed after admission were compared. Their clinical characteristics and experimental indicators were compared using SPSS software and R language to build a disease risk prediction model. Patients with condition changes after admission were older and had more blood cell abnormalities and impaired organ function (decreased albumin, elevated D-dimer) than normal patients. We found that age, neutrophil ratio, D-dimer, chest Computed tomograpgy (CT) changes, and glucocorticoid use were risk factors for COVID-19 pneumonia after admission. Elderly patients are more susceptible to disease changes after COVID-19 pneumonia; COVID-19 pneumonia patients who develop disease changes after admission have higher neutrophil ratios, increased D-dimer levels, chest imaging changes, and glucocorticoid usage. Additional research is needed. |
format | Online Article Text |
id | pubmed-7647591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-76475912020-11-09 Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China Jie, Li Shao Yu, Yuan Ping, Zeng Jian Dong, Xiang Xu Ping, Chai Xiang Chao, Hu Li, Yang Jing, Yang Ling, Tan Yan Yan, Jiang Ming Peng, Ling Medicine (Baltimore) 4900 Coronavirus disease 2019 (COVID-19) has spread worldwide, causing significant stress on the medical system. We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. The patients diagnosed with COVID-19 pneumonia at 2 medical centers in Hunan Province were studied, and those whose conditions changed after admission were compared. Their clinical characteristics and experimental indicators were compared using SPSS software and R language to build a disease risk prediction model. Patients with condition changes after admission were older and had more blood cell abnormalities and impaired organ function (decreased albumin, elevated D-dimer) than normal patients. We found that age, neutrophil ratio, D-dimer, chest Computed tomograpgy (CT) changes, and glucocorticoid use were risk factors for COVID-19 pneumonia after admission. Elderly patients are more susceptible to disease changes after COVID-19 pneumonia; COVID-19 pneumonia patients who develop disease changes after admission have higher neutrophil ratios, increased D-dimer levels, chest imaging changes, and glucocorticoid usage. Additional research is needed. Lippincott Williams & Wilkins 2020-11-06 /pmc/articles/PMC7647591/ /pubmed/33157941 http://dx.doi.org/10.1097/MD.0000000000022980 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections. |
spellingShingle | 4900 Jie, Li Shao Yu, Yuan Ping, Zeng Jian Dong, Xiang Xu Ping, Chai Xiang Chao, Hu Li, Yang Jing, Yang Ling, Tan Yan Yan, Jiang Ming Peng, Ling Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title | Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title_full | Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title_fullStr | Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title_full_unstemmed | Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title_short | Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China |
title_sort | risk factors for coronavirus disease 2019 pneumonia after admission outside wuhan, china |
topic | 4900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647591/ https://www.ncbi.nlm.nih.gov/pubmed/33157941 http://dx.doi.org/10.1097/MD.0000000000022980 |
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