Chaperone‐mediated autophagy receptor modulates tumor growth and chemoresistance in non–small cell lung cancer

Chaperone‐mediated autophagy (CMA) is a lysosomal degradation pathway of selective soluble proteins. Lysosome‐associated membrane protein type 2a (LAMP2A) is the key receptor protein of CMA; downregulation of LAMP2A leads to CMA blockade. Although CMA activation has been involved in cancer growth, C...

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Detalles Bibliográficos
Autores principales: Ichikawa, Akihiro, Fujita, Yu, Hosaka, Yusuke, Kadota, Tsukasa, Ito, Akihiko, Yagishita, Shigehiro, Watanabe, Naoaki, Fujimoto, Shota, Kawamoto, Hironori, Saito, Nayuta, Yoshida, Masahiro, Hashimoto, Mitsuo, Minagawa, Shunsuke, Hara, Hiromichi, Motoi, Noriko, Yamamoto, Yusuke, Ochiya, Takahiro, Araya, Jun, Kuwano, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648026/
https://www.ncbi.nlm.nih.gov/pubmed/32860290
http://dx.doi.org/10.1111/cas.14629

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