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Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer

The purpose of this study was to evaluate the relationships of smoking, alcohol consumption, and obesity with thyroid cancer in Korean residents. The Korean National Health Insurance Service-Health Screening Cohort includes individuals ≥ 40 years who were assessed from 2002 to 2013. In total, 4977 t...

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Autores principales: An, Soo-Youn, Kim, So Young, Oh, Dong Jun, Min, Chanyang, Sim, Songyoung, Choi, Hyo Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648098/
https://www.ncbi.nlm.nih.gov/pubmed/33159164
http://dx.doi.org/10.1038/s41598-020-76357-y
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author An, Soo-Youn
Kim, So Young
Oh, Dong Jun
Min, Chanyang
Sim, Songyoung
Choi, Hyo Geun
author_facet An, Soo-Youn
Kim, So Young
Oh, Dong Jun
Min, Chanyang
Sim, Songyoung
Choi, Hyo Geun
author_sort An, Soo-Youn
collection PubMed
description The purpose of this study was to evaluate the relationships of smoking, alcohol consumption, and obesity with thyroid cancer in Korean residents. The Korean National Health Insurance Service-Health Screening Cohort includes individuals ≥ 40 years who were assessed from 2002 to 2013. In total, 4977 thyroid cancer participants were matched with respect to age, sex, income, and region of residence with 19,908 controls at a ratio of 1:4. Crude and adjusted (for the Charlson comorbidity index, smoking status, frequency of alcohol consumption, and obesity) odds ratios (ORs) were analyzed using conditional logistic regression analyses. Additionally, 95% confidence intervals (CIs) were calculated. The adjusted OR of smoking for thyroid cancer was 0.62 (95% CI 0.54–0.72, P < 0.001), and that of alcohol consumption was 0.83 (95% CI 0.75–0.92, P < 0.001). The adjusted ORs of the BMI categories were 1.13 (95% CI 1.05–1.22, P = 0.002) for obese I, and 1.24 (95% CI 1.04–1.47, P = 0.014) for obese II. The ORs of smoking and alcohol consumption were lower, and those of overweight and obesity were higher in thyroid cancer patients than in individuals in the control group.
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spelling pubmed-76480982020-11-12 Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer An, Soo-Youn Kim, So Young Oh, Dong Jun Min, Chanyang Sim, Songyoung Choi, Hyo Geun Sci Rep Article The purpose of this study was to evaluate the relationships of smoking, alcohol consumption, and obesity with thyroid cancer in Korean residents. The Korean National Health Insurance Service-Health Screening Cohort includes individuals ≥ 40 years who were assessed from 2002 to 2013. In total, 4977 thyroid cancer participants were matched with respect to age, sex, income, and region of residence with 19,908 controls at a ratio of 1:4. Crude and adjusted (for the Charlson comorbidity index, smoking status, frequency of alcohol consumption, and obesity) odds ratios (ORs) were analyzed using conditional logistic regression analyses. Additionally, 95% confidence intervals (CIs) were calculated. The adjusted OR of smoking for thyroid cancer was 0.62 (95% CI 0.54–0.72, P < 0.001), and that of alcohol consumption was 0.83 (95% CI 0.75–0.92, P < 0.001). The adjusted ORs of the BMI categories were 1.13 (95% CI 1.05–1.22, P = 0.002) for obese I, and 1.24 (95% CI 1.04–1.47, P = 0.014) for obese II. The ORs of smoking and alcohol consumption were lower, and those of overweight and obesity were higher in thyroid cancer patients than in individuals in the control group. Nature Publishing Group UK 2020-11-06 /pmc/articles/PMC7648098/ /pubmed/33159164 http://dx.doi.org/10.1038/s41598-020-76357-y Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
An, Soo-Youn
Kim, So Young
Oh, Dong Jun
Min, Chanyang
Sim, Songyoung
Choi, Hyo Geun
Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title_full Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title_fullStr Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title_full_unstemmed Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title_short Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
title_sort obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648098/
https://www.ncbi.nlm.nih.gov/pubmed/33159164
http://dx.doi.org/10.1038/s41598-020-76357-y
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