Cargando…
Pharmacological validation of targets regulating CD14 during macrophage differentiation
The signalling receptor for LPS, CD14, is a key marker of, and facilitator for, pro-inflammatory macrophage function. Pro-inflammatory macrophage differentiation remains a process facilitating a broad array of disease pathologies, and has recently emerged as a potential target against cytokine storm...
Autores principales: | Jimenez-Duran, Gisela, Luque-Martin, Rosario, Patel, Meghana, Koppe, Emma, Bernard, Sharon, Sharp, Catriona, Buchan, Natalie, Rea, Ceara, de Winther, Menno P.J., Turan, Nil, Angell, Davina, Wells, Christine A., Cousins, Rick, Mander, Palwinder K., Masters, Seth L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648121/ https://www.ncbi.nlm.nih.gov/pubmed/33038762 http://dx.doi.org/10.1016/j.ebiom.2020.103039 |
Ejemplares similares
-
Classic and new mediators for in vitro modelling of human macrophages
por: Luque‐Martin, Rosario, et al.
Publicado: (2020) -
Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration
por: Mander, Palwinder, et al.
Publicado: (2005) -
Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis
por: Luque-Martin, Rosario, et al.
Publicado: (2019) -
Macrophage subsets in atherosclerosis as defined by single‐cell technologies
por: Willemsen, Lisa, et al.
Publicado: (2020) -
Repressing the repressor: Ezh2 mediates macrophage activation
por: Neele, Annette E., et al.
Publicado: (2018)