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An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa

BACKGROUND: Mycobacterium tuberculosis (Mtb) infection is inferred from positive results of T-cell immune conversion assays measuring Mtb-specific interferon gamma production or tuberculin skin test (TST) reactivity. Certain exposed individuals do not display T-cell immune conversion in these assays...

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Detalles Bibliográficos
Autores principales: Kroon, Elouise E., Kinnear, Craig J., Orlova, Marianna, Fischinger, Stephanie, Shin, Sally, Boolay, Sihaam, Walzl, Gerhard, Jacobs, Ashley, Wilkinson, Robert J., Alter, Galit, Schurr, Erwin, Hoal, Eileen G., Möller, Marlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648124/
https://www.ncbi.nlm.nih.gov/pubmed/33038764
http://dx.doi.org/10.1016/j.ebiom.2020.103053