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The Effect of CDK6 Expression on DNA Methylation and DNMT3B Regulation
CDK6 is frequently overexpressed in various cancer types and functions as a positive regulator of the cell cycle and as a coregulator of gene transcription. We provide evidence that CDK6 is involved in the process of DNA methylation, at least in ALL. We observe a positive correlation of CDK6 and DNM...
Autores principales: | Heller, Gerwin, Nebenfuehr, Sofie, Bellutti, Florian, Ünal, Huriye, Zojer, Markus, Scheiblecker, Lisa, Sexl, Veronika, Kollmann, Karoline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648139/ https://www.ncbi.nlm.nih.gov/pubmed/33205015 http://dx.doi.org/10.1016/j.isci.2020.101602 |
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