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Ocular Manifestations of Sarcoidosis in a South Florida Population
OBJECTIVE: To describe the ocular manifestations of sarcoidosis in a South Florida population and identify risk factors for the presence of ocular disease. DESIGN: Retrospective consecutive case series. METHODS: Medical charts of individuals with sarcoidosis seen in the University of Miami pulmonary...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648141/ https://www.ncbi.nlm.nih.gov/pubmed/33173272 http://dx.doi.org/10.2147/OPTH.S278373 |
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author | Laura, Diana Lee, Yonghoon Farhangi, Monika Salamo, Oriana Mirsaeidi, Mehdi Goldhardt, Raquel Galor, Anat |
author_facet | Laura, Diana Lee, Yonghoon Farhangi, Monika Salamo, Oriana Mirsaeidi, Mehdi Goldhardt, Raquel Galor, Anat |
author_sort | Laura, Diana |
collection | PubMed |
description | OBJECTIVE: To describe the ocular manifestations of sarcoidosis in a South Florida population and identify risk factors for the presence of ocular disease. DESIGN: Retrospective consecutive case series. METHODS: Medical charts of individuals with sarcoidosis seen in the University of Miami pulmonary department were reviewed for ocular disease. Odds ratios were used to identify risk factors for ocular sarcoidosis. RESULTS: Fourteen of 108 individuals with sarcoidosis had ocular involvement. The mean age of the 14 individuals was 56±15 years. Seventy-one percent were female, 50% were black, and 21% were Hispanic. Twelve had uveitis of which panuveitis was the most common subtype. Five had ≤20/70 vision in at least one eye due to uveitis. Neurosarcoidosis was a risk factor for ocular sarcoidosis (OR 6.14, p=0.03, 95% CI 1.21–31.09). CONCLUSION: Ocular manifestations occurred in a minority of individuals in a pulmonary sarcoidosis clinic in South Florida. Uveitis was the most common ocular manifestation. Neurosarcoidosis was a risk factor for ocular involvement. |
format | Online Article Text |
id | pubmed-7648141 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-76481412020-11-09 Ocular Manifestations of Sarcoidosis in a South Florida Population Laura, Diana Lee, Yonghoon Farhangi, Monika Salamo, Oriana Mirsaeidi, Mehdi Goldhardt, Raquel Galor, Anat Clin Ophthalmol Original Research OBJECTIVE: To describe the ocular manifestations of sarcoidosis in a South Florida population and identify risk factors for the presence of ocular disease. DESIGN: Retrospective consecutive case series. METHODS: Medical charts of individuals with sarcoidosis seen in the University of Miami pulmonary department were reviewed for ocular disease. Odds ratios were used to identify risk factors for ocular sarcoidosis. RESULTS: Fourteen of 108 individuals with sarcoidosis had ocular involvement. The mean age of the 14 individuals was 56±15 years. Seventy-one percent were female, 50% were black, and 21% were Hispanic. Twelve had uveitis of which panuveitis was the most common subtype. Five had ≤20/70 vision in at least one eye due to uveitis. Neurosarcoidosis was a risk factor for ocular sarcoidosis (OR 6.14, p=0.03, 95% CI 1.21–31.09). CONCLUSION: Ocular manifestations occurred in a minority of individuals in a pulmonary sarcoidosis clinic in South Florida. Uveitis was the most common ocular manifestation. Neurosarcoidosis was a risk factor for ocular involvement. Dove 2020-11-02 /pmc/articles/PMC7648141/ /pubmed/33173272 http://dx.doi.org/10.2147/OPTH.S278373 Text en © 2020 Laura et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Laura, Diana Lee, Yonghoon Farhangi, Monika Salamo, Oriana Mirsaeidi, Mehdi Goldhardt, Raquel Galor, Anat Ocular Manifestations of Sarcoidosis in a South Florida Population |
title | Ocular Manifestations of Sarcoidosis in a South Florida Population |
title_full | Ocular Manifestations of Sarcoidosis in a South Florida Population |
title_fullStr | Ocular Manifestations of Sarcoidosis in a South Florida Population |
title_full_unstemmed | Ocular Manifestations of Sarcoidosis in a South Florida Population |
title_short | Ocular Manifestations of Sarcoidosis in a South Florida Population |
title_sort | ocular manifestations of sarcoidosis in a south florida population |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648141/ https://www.ncbi.nlm.nih.gov/pubmed/33173272 http://dx.doi.org/10.2147/OPTH.S278373 |
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