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Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines
BACKGROUND: Hi-C and its variant techniques have been developed to capture the spatial organization of chromatin. Normalization of Hi-C contact map is essential for accurate modeling and interpretation of high-throughput chromatin conformation capture (3C) experiments. Hi-C correction tools were ori...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648276/ https://www.ncbi.nlm.nih.gov/pubmed/33160308 http://dx.doi.org/10.1186/s12859-020-03832-8 |