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Developmental programming: gestational testosterone excess disrupts LH secretion in the female sheep fetus

BACKGROUND: Prenatal testosterone (T) excess results in reproductive and metabolic perturbations in female sheep that closely recapitulate those seen in women with polycystic ovary syndrome (PCOS). At the neuroendocrine level, prenatal T-treated sheep manifest increased pituitary sensitivity to GnRH...

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Detalles Bibliográficos
Autores principales:	Landers, Renata S. M., Padmanabhan, Vasantha, Cardoso, Rodolfo C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648305/ https://www.ncbi.nlm.nih.gov/pubmed/33158439 http://dx.doi.org/10.1186/s12958-020-00667-z

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