Genomic Alterations of NTRK, POLE, ERBB2, and Microsatellite Instability Status in Chinese Patients with Colorectal Cancer

BACKGROUND: The increasing molecular characterization of colorectal cancers (CRCs) has spurred the need to look beyond RAS, BRAF, and microsatellite instability (MSI). Genomic alterations, including ERBB2 amplifications and mutations, POLE mutations, MSI, and NTRK1–3 fusions, have emerged as targets...

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Detalles Bibliográficos
Autores principales: Guo, Yun, Guo, Xian‐ling, Wang, Shuang, Chen, Xinyu, Shi, Jiaochun, Wang, Jian, Wang, Kai, Klempner, Samuel J., Wang, Weifeng, Xiao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Cancer Diagnostics and Molecular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648350/
https://www.ncbi.nlm.nih.gov/pubmed/32627883
http://dx.doi.org/10.1634/theoncologist.2020-0356

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