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Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG

BACKGROUND: Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated by cross-reacting with neuronal surface P antigen (NSPA)...

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Detalles Bibliográficos
Autores principales:	Espinoza, Sofía, Arredondo, Sebastián B., Barake, Francisca, Carvajal, Francisco, Guerrero, Fernanda G., Segovia-Miranda, Fabian, Valenzuela, David M., Wyneken, Ursula, Rojas-Fernández, Alejandro, Cerpa, Waldo, Massardo, Loreto, Varela-Nallar, Lorena, González, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648380/ https://www.ncbi.nlm.nih.gov/pubmed/33158444 http://dx.doi.org/10.1186/s12915-020-00877-2

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