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A model of k-mer surprisal to quantify local sequence information content surrounding splice regions

Molecular sequences carry information. Analysis of sequence conservation between homologous loci is a proven approach with which to explore the information content of molecular sequences. This is often done using multiple sequence alignments to support comparisons between homologous loci. These meth...

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Detalles Bibliográficos
Autores principales: Humphrey, Sam, Kerr, Alastair, Rattray, Magnus, Dive, Caroline, Miller, Crispin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648452/
https://www.ncbi.nlm.nih.gov/pubmed/33194378
http://dx.doi.org/10.7717/peerj.10063