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Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel
OBJECTIVE: To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR test resul...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648555/ https://www.ncbi.nlm.nih.gov/pubmed/33160412 http://dx.doi.org/10.1186/s13104-020-05365-y |
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author | Ogawa, Yoshihiko Nishida, Koji Gohma, Iwao Kasahara, Kei Yano, Hisakazu |
author_facet | Ogawa, Yoshihiko Nishida, Koji Gohma, Iwao Kasahara, Kei Yano, Hisakazu |
author_sort | Ogawa, Yoshihiko |
collection | PubMed |
description | OBJECTIVE: To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative PCR results. RESULTS: We studied a total of 15 HCP who had contact exposures (15/15) and aerosol exposures (7/15). None of them tested positive for IgG against SARS-CoV-2 on blood examination. None of them had any symptoms during 10 days of active isolation. All PCR tests conducted using the nasopharyngeal swabs collected from the HCP on day 10 were negative. No apparent infection was found in any of the HCP who had contact exposure with and/or aerosol exposure to the patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative results of PCR tests for SARS-CoV-2. Clinical trial: Trial Registration: No. 170, approved June 10th, 2020 by the ethics committee of Sakai City Medical Center. |
format | Online Article Text |
id | pubmed-7648555 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-76485552020-11-09 Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel Ogawa, Yoshihiko Nishida, Koji Gohma, Iwao Kasahara, Kei Yano, Hisakazu BMC Res Notes Research Note OBJECTIVE: To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative PCR results. RESULTS: We studied a total of 15 HCP who had contact exposures (15/15) and aerosol exposures (7/15). None of them tested positive for IgG against SARS-CoV-2 on blood examination. None of them had any symptoms during 10 days of active isolation. All PCR tests conducted using the nasopharyngeal swabs collected from the HCP on day 10 were negative. No apparent infection was found in any of the HCP who had contact exposure with and/or aerosol exposure to the patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative results of PCR tests for SARS-CoV-2. Clinical trial: Trial Registration: No. 170, approved June 10th, 2020 by the ethics committee of Sakai City Medical Center. BioMed Central 2020-11-07 /pmc/articles/PMC7648555/ /pubmed/33160412 http://dx.doi.org/10.1186/s13104-020-05365-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Note Ogawa, Yoshihiko Nishida, Koji Gohma, Iwao Kasahara, Kei Yano, Hisakazu Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title | Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_full | Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_fullStr | Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_full_unstemmed | Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_short | Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_sort | assessing the effects of exposure to a sars-cov-2 re-positive patient in healthcare personnel |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648555/ https://www.ncbi.nlm.nih.gov/pubmed/33160412 http://dx.doi.org/10.1186/s13104-020-05365-y |
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