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UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest

Translation arrest is a part of the cellular stress response that decreases energy consumption and enables rapid reprioritisation of gene expression. Often translation arrest leads to condensation of untranslated messenger ribonucleoproteins (mRNPs) into stress granules (SGs). Studies into mechanism...

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Detalles Bibliográficos
Autores principales: Ying, Shan, Khaperskyy, Denys A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648617/
https://www.ncbi.nlm.nih.gov/pubmed/32989041
http://dx.doi.org/10.1242/jcs.248310

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