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Besifloxacin liposomes with positively charged additives for an improved topical ocular delivery

Topical ophthalmic antibiotics show low efficacy due to the well-known physiological defense mechanisms of the eye, which prevents the penetration of exogenous substances. Here, we aimed to incorporate besifloxacin into liposomes containing amines as positively charged additives and to evaluate the...

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Detalles Bibliográficos
Autores principales:	dos Santos, Giselly Almeida, Ferreira-Nunes, Ricardo, Dalmolin, Luciana Facco, dos Santos Ré, Ana Carolina, Anjos, Jorge Luiz Vieira, Mendanha, Sebastião Antônio, Aires, Carolina Patrícia, Lopez, Renata F. V., Cunha-Filho, Marcilio, Gelfuso, Guilherme M., Gratieri, Taís
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648625/ https://www.ncbi.nlm.nih.gov/pubmed/33159142 http://dx.doi.org/10.1038/s41598-020-76381-y

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