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Nickel-catalyzed reductive coupling of homoenolates and their higher homologues with unactivated alkyl bromides

The catalytic generation of homoenolates and their higher homologues has been a long-standing challenge. Like the generation of transition metal enolates, which have been used to great affect in synthesis and medicinal chemistries, homoenolates and their higher homologues have much potential, albeit...

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Detalles Bibliográficos
Autores principales: Lin, Tingzhi, Gu, Yuanyun, Qian, Pengcheng, Guan, Haixing, Walsh, Patrick J., Mao, Jianyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648641/
https://www.ncbi.nlm.nih.gov/pubmed/33159055
http://dx.doi.org/10.1038/s41467-020-19194-x