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Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway

The bone marrow microenvironment plays important roles in the progression of the myelodysplastic syndrome (MDS). The higher incidence of ASXL1 and TET2 gene mutations in our iron overload (IO) MDS patients suggests that IO may be involved in the pathogenesis of MDS. The effects of IO damaging bone m...

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Detalles Bibliográficos
Autores principales:	Huang, Lei, Liu, Zhaoyun, Liu, Hui, Ding, Kai, Mi, Fu, Xiang, Chenhuan, Wang, Guanrou, Guo, Yixuan, Fu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648692/ https://www.ncbi.nlm.nih.gov/pubmed/33178287 http://dx.doi.org/10.1155/2020/8855038

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