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Impact of the first Covid-19 outbreak on liver transplantation activity in France: A snapshot

BACKGROUND: The global pandemic of Coronavirus Disease 2019 (COVID-19) has potentially affected liver transplantation (LT) programs worldwide. The aim of this study was to determine whether the COVID-19 outbreak affected organ donation and LT activity in France. METHODS: Data on the number of brain-...

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Detalles Bibliográficos
Autores principales: Turco, Célia, Lim, Chetana, Soubrane, Olivier, Malaquin, Géraldine, Kerbaul, François, Bastien, Olivier, Conti, Filomena, Scatton, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649029/
https://www.ncbi.nlm.nih.gov/pubmed/33176991
http://dx.doi.org/10.1016/j.clinre.2020.10.005
Descripción
Sumario:BACKGROUND: The global pandemic of Coronavirus Disease 2019 (COVID-19) has potentially affected liver transplantation (LT) programs worldwide. The aim of this study was to determine whether the COVID-19 outbreak affected organ donation and LT activity in France. METHODS: Data on the number of brain-dead donor procurements and adult liver transplantations were compared between two periods (1(st) January- 31(st) May 2019 vs. 1(st) January-31(st) May 2020). MAIN FINDINGS: There was a 28% decrease in the number of organ donations in 2020 (543 in 2020vs. 752 organ donations in 2019). A 22% decrease in the number of liver transplantations was also observed: 435 in 2020 vs. 556 LTs in 2019. Overall, the North East area which was the main COVID-19 cluster area, had > 25% decrease of the multiorgan procurement (-33% compared to 2019), and liver transplantation (-26% compared to 2019) activities in 2020 CONCLUSION: This analysis confirmed that during the COVID-19 outbreak there was a significant decrease in the number of organ donations and liver transplantations performed in France.