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Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis, tumor growth, and the production of antioxidants through glutaminolysis in cancers. In glutamine dependent cancer cells, mor...

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Detalles Bibliográficos
Autores principales: Wang, Zhefang, Liu, Fanyu, Fan, Ningbo, Zhou, Chenghui, Li, Dai, Macvicar, Thomas, Dong, Qiongzhu, Bruns, Christiane J., Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649373/
https://www.ncbi.nlm.nih.gov/pubmed/33194749
http://dx.doi.org/10.3389/fonc.2020.589508

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