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Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs

Platelet-rich plasma (PRP) is known to play a crucial role in skin wound healing, in both Human and Veterinary Medicine. Remarkably, until now, no studies have reported PRP treatment in subacute full-thickness skin wounds of the dog. The aim of this study was to evaluate the effects of two consecuti...

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Autores principales: Iacopetti, Ilaria, Patruno, Marco, Melotti, Luca, Martinello, Tiziana, Bedin, Silvia, Badon, Tamara, Righetto, Edoardo Maria, Perazzi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649378/
https://www.ncbi.nlm.nih.gov/pubmed/33195571
http://dx.doi.org/10.3389/fvets.2020.575449
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author Iacopetti, Ilaria
Patruno, Marco
Melotti, Luca
Martinello, Tiziana
Bedin, Silvia
Badon, Tamara
Righetto, Edoardo Maria
Perazzi, Anna
author_facet Iacopetti, Ilaria
Patruno, Marco
Melotti, Luca
Martinello, Tiziana
Bedin, Silvia
Badon, Tamara
Righetto, Edoardo Maria
Perazzi, Anna
author_sort Iacopetti, Ilaria
collection PubMed
description Platelet-rich plasma (PRP) is known to play a crucial role in skin wound healing, in both Human and Veterinary Medicine. Remarkably, until now, no studies have reported PRP treatment in subacute full-thickness skin wounds of the dog. The aim of this study was to evaluate the effects of two consecutive applications of autologous PRP, with the second application after 15 days, in 6 dogs showing large subacute skin wounds. The percentage of contraction, re-epithelialization and healing in all treated patients indicated that no complications or side effects, associated with consecutive PRP treatments, occurred in any patient and all wounds achieved complete closure and re-epithelialization. Our results suggest a positive effect of repeated autologous topical PRP treatments in large cutaneous subacute wounds of different etiology. Therefore, this PRP treatment could represent a simple, cost-effective, and valid alternative to promote healing processes in subacute large wounds cases in dogs.
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spelling pubmed-76493782020-11-13 Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs Iacopetti, Ilaria Patruno, Marco Melotti, Luca Martinello, Tiziana Bedin, Silvia Badon, Tamara Righetto, Edoardo Maria Perazzi, Anna Front Vet Sci Veterinary Science Platelet-rich plasma (PRP) is known to play a crucial role in skin wound healing, in both Human and Veterinary Medicine. Remarkably, until now, no studies have reported PRP treatment in subacute full-thickness skin wounds of the dog. The aim of this study was to evaluate the effects of two consecutive applications of autologous PRP, with the second application after 15 days, in 6 dogs showing large subacute skin wounds. The percentage of contraction, re-epithelialization and healing in all treated patients indicated that no complications or side effects, associated with consecutive PRP treatments, occurred in any patient and all wounds achieved complete closure and re-epithelialization. Our results suggest a positive effect of repeated autologous topical PRP treatments in large cutaneous subacute wounds of different etiology. Therefore, this PRP treatment could represent a simple, cost-effective, and valid alternative to promote healing processes in subacute large wounds cases in dogs. Frontiers Media S.A. 2020-10-26 /pmc/articles/PMC7649378/ /pubmed/33195571 http://dx.doi.org/10.3389/fvets.2020.575449 Text en Copyright © 2020 Iacopetti, Patruno, Melotti, Martinello, Bedin, Badon, Righetto and Perazzi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Iacopetti, Ilaria
Patruno, Marco
Melotti, Luca
Martinello, Tiziana
Bedin, Silvia
Badon, Tamara
Righetto, Edoardo Maria
Perazzi, Anna
Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title_full Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title_fullStr Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title_full_unstemmed Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title_short Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs
title_sort autologous platelet-rich plasma enhances the healing of large cutaneous wounds in dogs
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649378/
https://www.ncbi.nlm.nih.gov/pubmed/33195571
http://dx.doi.org/10.3389/fvets.2020.575449
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