Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt’s disease and dry age‐related macular degeneration

Age‐related macular degeneration (AMD) is the leading cause of blindness in older people in the developed world while Stargardt's disease (SD) is a juvenile macular degeneration and an orphan disease. Both diseases are untreatable and are marked by accumulation of lipofuscin advancing to progre...

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Detalles Bibliográficos
Autores principales: Julien‐Schraermeyer, Sylvie, Illing, Barbara, Tschulakow, Alexander, Taubitz, Tatjana, Guezguez, Jamil, Burnet, Michael, Schraermeyer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Invited Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649431/
https://www.ncbi.nlm.nih.gov/pubmed/33164337
http://dx.doi.org/10.1002/prp2.683

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