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COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respirato...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649511/ https://www.ncbi.nlm.nih.gov/pubmed/33204989 http://dx.doi.org/10.1093/ehjcr/ytaa276 |
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author | Kaplan, Jason G Kanwal, Arjun Malek, Ryan Dickey, John Q Keirn, Richard Zweig, Bryan Minter, David |
author_facet | Kaplan, Jason G Kanwal, Arjun Malek, Ryan Dickey, John Q Keirn, Richard Zweig, Bryan Minter, David |
author_sort | Kaplan, Jason G |
collection | PubMed |
description | BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respiratory failure requiring endotracheal intubation from her infection with SARS-CoV-2. This patient was subsequently found to have a right ventricular thrombus and bilateral pulmonary emboli, likely contributing to her respiratory status. On the 14th day of hospitalization, the patient was successfully extubated, and 5 days later was discharged to the rehabilitation unit. DISCUSSION: SARS-CoV-2 presents primarily with pulmonary symptoms; however, many patients, particularly those who are severely ill, exhibit adverse events related to hypercoagulability. The exact mechanism explaining this hypercoagulable state has yet to be elucidated, but these thrombotic events have been linked to the increased inflammation caused by SARS-CoV-2. This novel viral illness is still largely misunderstood, but the hypercoagulable state, seen in severely ill patients, appears to play a major role in disease progression and prognosis. |
format | Online Article Text |
id | pubmed-7649511 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-76495112020-11-16 COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report Kaplan, Jason G Kanwal, Arjun Malek, Ryan Dickey, John Q Keirn, Richard Zweig, Bryan Minter, David Eur Heart J Case Rep Case Reports BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respiratory failure requiring endotracheal intubation from her infection with SARS-CoV-2. This patient was subsequently found to have a right ventricular thrombus and bilateral pulmonary emboli, likely contributing to her respiratory status. On the 14th day of hospitalization, the patient was successfully extubated, and 5 days later was discharged to the rehabilitation unit. DISCUSSION: SARS-CoV-2 presents primarily with pulmonary symptoms; however, many patients, particularly those who are severely ill, exhibit adverse events related to hypercoagulability. The exact mechanism explaining this hypercoagulable state has yet to be elucidated, but these thrombotic events have been linked to the increased inflammation caused by SARS-CoV-2. This novel viral illness is still largely misunderstood, but the hypercoagulable state, seen in severely ill patients, appears to play a major role in disease progression and prognosis. Oxford University Press 2020-10-02 /pmc/articles/PMC7649511/ /pubmed/33204989 http://dx.doi.org/10.1093/ehjcr/ytaa276 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Reports Kaplan, Jason G Kanwal, Arjun Malek, Ryan Dickey, John Q Keirn, Richard Zweig, Bryan Minter, David COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title | COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title_full | COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title_fullStr | COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title_full_unstemmed | COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title_short | COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report |
title_sort | covid-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649511/ https://www.ncbi.nlm.nih.gov/pubmed/33204989 http://dx.doi.org/10.1093/ehjcr/ytaa276 |
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