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COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report

BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respirato...

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Autores principales: Kaplan, Jason G, Kanwal, Arjun, Malek, Ryan, Dickey, John Q, Keirn, Richard, Zweig, Bryan, Minter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649511/
https://www.ncbi.nlm.nih.gov/pubmed/33204989
http://dx.doi.org/10.1093/ehjcr/ytaa276
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author Kaplan, Jason G
Kanwal, Arjun
Malek, Ryan
Dickey, John Q
Keirn, Richard
Zweig, Bryan
Minter, David
author_facet Kaplan, Jason G
Kanwal, Arjun
Malek, Ryan
Dickey, John Q
Keirn, Richard
Zweig, Bryan
Minter, David
author_sort Kaplan, Jason G
collection PubMed
description BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respiratory failure requiring endotracheal intubation from her infection with SARS-CoV-2. This patient was subsequently found to have a right ventricular thrombus and bilateral pulmonary emboli, likely contributing to her respiratory status. On the 14th day of hospitalization, the patient was successfully extubated, and 5 days later was discharged to the rehabilitation unit. DISCUSSION: SARS-CoV-2 presents primarily with pulmonary symptoms; however, many patients, particularly those who are severely ill, exhibit adverse events related to hypercoagulability. The exact mechanism explaining this hypercoagulable state has yet to be elucidated, but these thrombotic events have been linked to the increased inflammation caused by SARS-CoV-2. This novel viral illness is still largely misunderstood, but the hypercoagulable state, seen in severely ill patients, appears to play a major role in disease progression and prognosis.
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spelling pubmed-76495112020-11-16 COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report Kaplan, Jason G Kanwal, Arjun Malek, Ryan Dickey, John Q Keirn, Richard Zweig, Bryan Minter, David Eur Heart J Case Rep Case Reports BACKGROUND: SARS-CoV-2 is a novel viral illness originating out of Wuhan China in late 2019. This global pandemic has infected nearly 3 million people and accounted for 200 000 deaths worldwide, with those numbers still climbing. CASE SUMMARY: We present a 54-year-old patient who developed respiratory failure requiring endotracheal intubation from her infection with SARS-CoV-2. This patient was subsequently found to have a right ventricular thrombus and bilateral pulmonary emboli, likely contributing to her respiratory status. On the 14th day of hospitalization, the patient was successfully extubated, and 5 days later was discharged to the rehabilitation unit. DISCUSSION: SARS-CoV-2 presents primarily with pulmonary symptoms; however, many patients, particularly those who are severely ill, exhibit adverse events related to hypercoagulability. The exact mechanism explaining this hypercoagulable state has yet to be elucidated, but these thrombotic events have been linked to the increased inflammation caused by SARS-CoV-2. This novel viral illness is still largely misunderstood, but the hypercoagulable state, seen in severely ill patients, appears to play a major role in disease progression and prognosis. Oxford University Press 2020-10-02 /pmc/articles/PMC7649511/ /pubmed/33204989 http://dx.doi.org/10.1093/ehjcr/ytaa276 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Kaplan, Jason G
Kanwal, Arjun
Malek, Ryan
Dickey, John Q
Keirn, Richard
Zweig, Bryan
Minter, David
COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title_full COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title_fullStr COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title_full_unstemmed COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title_short COVID-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? A case report
title_sort covid-19 resulting in bilateral pulmonary emboli and a right ventricular thrombus: association or causation? a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649511/
https://www.ncbi.nlm.nih.gov/pubmed/33204989
http://dx.doi.org/10.1093/ehjcr/ytaa276
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