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A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lowe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649619/ https://www.ncbi.nlm.nih.gov/pubmed/33204633 http://dx.doi.org/10.1016/j.idcr.2020.e01001 |
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author | Mazlan, Mohd Zulfakar Zainal Abidin, Huda Wan Hassan, Wan Mohd Nazaruddin Nik Mohamad, Nik Abdullah Salmuna, Zeti Norfidiyati Ibrahim, Kamaruddin Omar, Mahamarowi Abdul-Aziz, Mohd Hafiz |
author_facet | Mazlan, Mohd Zulfakar Zainal Abidin, Huda Wan Hassan, Wan Mohd Nazaruddin Nik Mohamad, Nik Abdullah Salmuna, Zeti Norfidiyati Ibrahim, Kamaruddin Omar, Mahamarowi Abdul-Aziz, Mohd Hafiz |
author_sort | Mazlan, Mohd Zulfakar |
collection | PubMed |
description | We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lower limb with no systemic manifestations. There was no discharge and bullae from the swelling area of the leg. He had high blood sugar and was newly diagnosed with type 2 diabetes mellitus. He was diagnosed with necrotizing fasciitis. An intravenous imipenem-cilastatin 500 mg every 6 h together with clindamycin 900 mg every 8 h was started empirically. Extensive wound debridement was performed. The swab culture obtained intraoperatively grew Pseudomonas aeruginosa. He required an above knee amputation due to worsening infection despite wound debridement. Post-operatively, he developed acute kidney injury with severe metabolic acidosis, which required daily hemodialysis. However, the patient deteriorated due to septic shock with multi-organ failure, resulting in his death. |
format | Online Article Text |
id | pubmed-7649619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-76496192020-11-16 A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal Mazlan, Mohd Zulfakar Zainal Abidin, Huda Wan Hassan, Wan Mohd Nazaruddin Nik Mohamad, Nik Abdullah Salmuna, Zeti Norfidiyati Ibrahim, Kamaruddin Omar, Mahamarowi Abdul-Aziz, Mohd Hafiz IDCases Case Report We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lower limb with no systemic manifestations. There was no discharge and bullae from the swelling area of the leg. He had high blood sugar and was newly diagnosed with type 2 diabetes mellitus. He was diagnosed with necrotizing fasciitis. An intravenous imipenem-cilastatin 500 mg every 6 h together with clindamycin 900 mg every 8 h was started empirically. Extensive wound debridement was performed. The swab culture obtained intraoperatively grew Pseudomonas aeruginosa. He required an above knee amputation due to worsening infection despite wound debridement. Post-operatively, he developed acute kidney injury with severe metabolic acidosis, which required daily hemodialysis. However, the patient deteriorated due to septic shock with multi-organ failure, resulting in his death. Elsevier 2020-11-02 /pmc/articles/PMC7649619/ /pubmed/33204633 http://dx.doi.org/10.1016/j.idcr.2020.e01001 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Mazlan, Mohd Zulfakar Zainal Abidin, Huda Wan Hassan, Wan Mohd Nazaruddin Nik Mohamad, Nik Abdullah Salmuna, Zeti Norfidiyati Ibrahim, Kamaruddin Omar, Mahamarowi Abdul-Aziz, Mohd Hafiz A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title | A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title_full | A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title_fullStr | A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title_full_unstemmed | A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title_short | A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
title_sort | case report: community-acquired pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649619/ https://www.ncbi.nlm.nih.gov/pubmed/33204633 http://dx.doi.org/10.1016/j.idcr.2020.e01001 |
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