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A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal

We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lowe...

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Autores principales: Mazlan, Mohd Zulfakar, Zainal Abidin, Huda, Wan Hassan, Wan Mohd Nazaruddin, Nik Mohamad, Nik Abdullah, Salmuna, Zeti Norfidiyati, Ibrahim, Kamaruddin, Omar, Mahamarowi, Abdul-Aziz, Mohd Hafiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649619/
https://www.ncbi.nlm.nih.gov/pubmed/33204633
http://dx.doi.org/10.1016/j.idcr.2020.e01001
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author Mazlan, Mohd Zulfakar
Zainal Abidin, Huda
Wan Hassan, Wan Mohd Nazaruddin
Nik Mohamad, Nik Abdullah
Salmuna, Zeti Norfidiyati
Ibrahim, Kamaruddin
Omar, Mahamarowi
Abdul-Aziz, Mohd Hafiz
author_facet Mazlan, Mohd Zulfakar
Zainal Abidin, Huda
Wan Hassan, Wan Mohd Nazaruddin
Nik Mohamad, Nik Abdullah
Salmuna, Zeti Norfidiyati
Ibrahim, Kamaruddin
Omar, Mahamarowi
Abdul-Aziz, Mohd Hafiz
author_sort Mazlan, Mohd Zulfakar
collection PubMed
description We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lower limb with no systemic manifestations. There was no discharge and bullae from the swelling area of the leg. He had high blood sugar and was newly diagnosed with type 2 diabetes mellitus. He was diagnosed with necrotizing fasciitis. An intravenous imipenem-cilastatin 500 mg every 6 h together with clindamycin 900 mg every 8 h was started empirically. Extensive wound debridement was performed. The swab culture obtained intraoperatively grew Pseudomonas aeruginosa. He required an above knee amputation due to worsening infection despite wound debridement. Post-operatively, he developed acute kidney injury with severe metabolic acidosis, which required daily hemodialysis. However, the patient deteriorated due to septic shock with multi-organ failure, resulting in his death.
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spelling pubmed-76496192020-11-16 A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal Mazlan, Mohd Zulfakar Zainal Abidin, Huda Wan Hassan, Wan Mohd Nazaruddin Nik Mohamad, Nik Abdullah Salmuna, Zeti Norfidiyati Ibrahim, Kamaruddin Omar, Mahamarowi Abdul-Aziz, Mohd Hafiz IDCases Case Report We present a case study of a 26-year-old morbidly obese man with a three-day history of right leg pain and swelling. The swelling was associated with low grade fever. He was alert and conscious upon presentation to the hospital. His physical examination showed gross swelling of the entire right lower limb with no systemic manifestations. There was no discharge and bullae from the swelling area of the leg. He had high blood sugar and was newly diagnosed with type 2 diabetes mellitus. He was diagnosed with necrotizing fasciitis. An intravenous imipenem-cilastatin 500 mg every 6 h together with clindamycin 900 mg every 8 h was started empirically. Extensive wound debridement was performed. The swab culture obtained intraoperatively grew Pseudomonas aeruginosa. He required an above knee amputation due to worsening infection despite wound debridement. Post-operatively, he developed acute kidney injury with severe metabolic acidosis, which required daily hemodialysis. However, the patient deteriorated due to septic shock with multi-organ failure, resulting in his death. Elsevier 2020-11-02 /pmc/articles/PMC7649619/ /pubmed/33204633 http://dx.doi.org/10.1016/j.idcr.2020.e01001 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Mazlan, Mohd Zulfakar
Zainal Abidin, Huda
Wan Hassan, Wan Mohd Nazaruddin
Nik Mohamad, Nik Abdullah
Salmuna, Zeti Norfidiyati
Ibrahim, Kamaruddin
Omar, Mahamarowi
Abdul-Aziz, Mohd Hafiz
A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title_full A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title_fullStr A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title_full_unstemmed A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title_short A case report: Community-acquired Pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
title_sort case report: community-acquired pseudomonas aeruginosa necrotizing fasciitis in a morbidly obese diabetic young man can be fatal
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649619/
https://www.ncbi.nlm.nih.gov/pubmed/33204633
http://dx.doi.org/10.1016/j.idcr.2020.e01001
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