Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India

• CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases. • The conventional stained smear and CB-NAAT results were compared to the MGIT culture. • Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%. • The rapid results from CB-NAAT confirms its use in t...

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Detalles Bibliográficos
Autores principales: Raj, Aishwarya, Baliga, Shrikala, Shenoy, M. Suchitra, Dhanashree, B., Mithra, P. Prasanna, Nambiar, Smitha K., Sharon, Leesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649623/
https://www.ncbi.nlm.nih.gov/pubmed/33204853
http://dx.doi.org/10.1016/j.jctube.2020.100198
Descripción
Sumario:• CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases. • The conventional stained smear and CB-NAAT results were compared to the MGIT culture. • Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%. • The rapid results from CB-NAAT confirms its use in the tuberculosis diagnostic algorithm. • The benefits of disease diagnosis and prevention outweighs the price tag of the CB-NAAT tests. • This is more so for the resource poor countries where the burden of the disease is high.

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