Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India

• CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases. • The conventional stained smear and CB-NAAT results were compared to the MGIT culture. • Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%. • The rapid results from CB-NAAT confirms its use in t...

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Autores principales: Raj, Aishwarya, Baliga, Shrikala, Shenoy, M. Suchitra, Dhanashree, B., Mithra, P. Prasanna, Nambiar, Smitha K., Sharon, Leesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649623/
https://www.ncbi.nlm.nih.gov/pubmed/33204853
http://dx.doi.org/10.1016/j.jctube.2020.100198
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author Raj, Aishwarya
Baliga, Shrikala
Shenoy, M. Suchitra
Dhanashree, B.
Mithra, P. Prasanna
Nambiar, Smitha K.
Sharon, Leesha
author_facet Raj, Aishwarya
Baliga, Shrikala
Shenoy, M. Suchitra
Dhanashree, B.
Mithra, P. Prasanna
Nambiar, Smitha K.
Sharon, Leesha
author_sort Raj, Aishwarya
collection PubMed
description • CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases. • The conventional stained smear and CB-NAAT results were compared to the MGIT culture. • Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%. • The rapid results from CB-NAAT confirms its use in the tuberculosis diagnostic algorithm. • The benefits of disease diagnosis and prevention outweighs the price tag of the CB-NAAT tests. • This is more so for the resource poor countries where the burden of the disease is high.
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spelling pubmed-76496232020-11-16 Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India Raj, Aishwarya Baliga, Shrikala Shenoy, M. Suchitra Dhanashree, B. Mithra, P. Prasanna Nambiar, Smitha K. Sharon, Leesha J Clin Tuberc Other Mycobact Dis Article • CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases. • The conventional stained smear and CB-NAAT results were compared to the MGIT culture. • Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%. • The rapid results from CB-NAAT confirms its use in the tuberculosis diagnostic algorithm. • The benefits of disease diagnosis and prevention outweighs the price tag of the CB-NAAT tests. • This is more so for the resource poor countries where the burden of the disease is high. Elsevier 2020-10-28 /pmc/articles/PMC7649623/ /pubmed/33204853 http://dx.doi.org/10.1016/j.jctube.2020.100198 Text en © 2020 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Raj, Aishwarya
Baliga, Shrikala
Shenoy, M. Suchitra
Dhanashree, B.
Mithra, P. Prasanna
Nambiar, Smitha K.
Sharon, Leesha
Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title_full Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title_fullStr Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title_full_unstemmed Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title_short Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India
title_sort validity of a cb-naat assay in diagnosing tuberculosis in comparison to culture: a study from an urban area of south india
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649623/
https://www.ncbi.nlm.nih.gov/pubmed/33204853
http://dx.doi.org/10.1016/j.jctube.2020.100198
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