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Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity

The ectonucleoside triphosphate diphosphohydrolase (CD39)/5′ ectonuclotidase (CD73)-dependent purinergic pathway emerges as promising cancer target. Yet, except for own previous work revealing a pathogenic role of CD73 and adenosine in radiation-induced lung fibrosis, the role of purinergic signalin...

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Detalles Bibliográficos
Autores principales:	Meyer, Alina V., Klein, Diana, de Leve, Simone, Szymonowicz, Klaudia, Stuschke, Martin, Robson, Simon C., Jendrossek, Verena, Wirsdörfer, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649817/ https://www.ncbi.nlm.nih.gov/pubmed/33194619 http://dx.doi.org/10.3389/fonc.2020.554883

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