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Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients

BACKGROUND: Diabetes mellitus is becoming one of the major health problems in developing countries. The number of adults living with type 2 diabetes mellitus (T2DM) worldwide is increasing over time. Cardiovascular disease (CVD) is the major cause of death in T2DM. The objective of this study was to...

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Autores principales: Tesfaye, Adane, Josef, Haileyesus, Wube, Temesgen Bizuayehu, Girma, Zeleke, Negasa, Belay, Muche, Temesgen, Zewude, Bewnetu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649970/
https://www.ncbi.nlm.nih.gov/pubmed/33177852
http://dx.doi.org/10.2147/DMSO.S254883
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author Tesfaye, Adane
Josef, Haileyesus
Wube, Temesgen Bizuayehu
Girma, Zeleke
Negasa, Belay
Muche, Temesgen
Zewude, Bewnetu
author_facet Tesfaye, Adane
Josef, Haileyesus
Wube, Temesgen Bizuayehu
Girma, Zeleke
Negasa, Belay
Muche, Temesgen
Zewude, Bewnetu
author_sort Tesfaye, Adane
collection PubMed
description BACKGROUND: Diabetes mellitus is becoming one of the major health problems in developing countries. The number of adults living with type 2 diabetes mellitus (T2DM) worldwide is increasing over time. Cardiovascular disease (CVD) is the major cause of death in T2DM. The objective of this study was to determine the prevalence of cardiovascular disease and its associated factors among diabetic patients at the MRC clinic of Dilla University Referral Hospital (DURH). METHODS: A hospital-based cross-sectional study was conducted from April to May 2019 . A total of 216 diabetic individuals were selected with a convenient sampling technique from patients on follow-up at DURH MRC. Data were collected using a structured format. The diagnosis of CVD was made with the necessary diagnostic tests and examination. The data analysis was done in SPSS software version 20. Bivariate and multivariable logistic regression analysis was carried out to identify factors associated with cardiovascular disease. RESULTS: A total of 216 patients participated in the study and the mean age of the study participants was 30 years; 83.3% of the study participants were male. The overall prevalence of cardiovascular disease was 25% of which 57% were ischemic heart disease, 32% were hypertensive and 10% were stroke. Duration of DM for more than 10 years and diabetic drug discontinuation were factors associated with cardiovascular disease. Odds of CVD was nearly four times more in those whose duration of DM is more than 10 years (AOR=4.00, 95% CI: 2.386–6.705) and odds of CVD among those who discontinued medication were almost three times more, (AOR=2.98, 95% CI: 1.287–6.080). CONCLUSION: A quarter of the diabetic population studied developed CVD. Duration of DM for more than 10 years and drug discontinuation are independent associated factors of CVD. Hence appropriate intervention at early stages should be implemented at primary healthcare level.
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spelling pubmed-76499702020-11-10 Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients Tesfaye, Adane Josef, Haileyesus Wube, Temesgen Bizuayehu Girma, Zeleke Negasa, Belay Muche, Temesgen Zewude, Bewnetu Diabetes Metab Syndr Obes Original Research BACKGROUND: Diabetes mellitus is becoming one of the major health problems in developing countries. The number of adults living with type 2 diabetes mellitus (T2DM) worldwide is increasing over time. Cardiovascular disease (CVD) is the major cause of death in T2DM. The objective of this study was to determine the prevalence of cardiovascular disease and its associated factors among diabetic patients at the MRC clinic of Dilla University Referral Hospital (DURH). METHODS: A hospital-based cross-sectional study was conducted from April to May 2019 . A total of 216 diabetic individuals were selected with a convenient sampling technique from patients on follow-up at DURH MRC. Data were collected using a structured format. The diagnosis of CVD was made with the necessary diagnostic tests and examination. The data analysis was done in SPSS software version 20. Bivariate and multivariable logistic regression analysis was carried out to identify factors associated with cardiovascular disease. RESULTS: A total of 216 patients participated in the study and the mean age of the study participants was 30 years; 83.3% of the study participants were male. The overall prevalence of cardiovascular disease was 25% of which 57% were ischemic heart disease, 32% were hypertensive and 10% were stroke. Duration of DM for more than 10 years and diabetic drug discontinuation were factors associated with cardiovascular disease. Odds of CVD was nearly four times more in those whose duration of DM is more than 10 years (AOR=4.00, 95% CI: 2.386–6.705) and odds of CVD among those who discontinued medication were almost three times more, (AOR=2.98, 95% CI: 1.287–6.080). CONCLUSION: A quarter of the diabetic population studied developed CVD. Duration of DM for more than 10 years and drug discontinuation are independent associated factors of CVD. Hence appropriate intervention at early stages should be implemented at primary healthcare level. Dove 2020-11-03 /pmc/articles/PMC7649970/ /pubmed/33177852 http://dx.doi.org/10.2147/DMSO.S254883 Text en © 2020 Tesfaye et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Tesfaye, Adane
Josef, Haileyesus
Wube, Temesgen Bizuayehu
Girma, Zeleke
Negasa, Belay
Muche, Temesgen
Zewude, Bewnetu
Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_full Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_fullStr Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_full_unstemmed Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_short Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_sort magnitude of, and factors associated with cardiovascular disease among type two diabetes mellitus patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649970/
https://www.ncbi.nlm.nih.gov/pubmed/33177852
http://dx.doi.org/10.2147/DMSO.S254883
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