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Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are constantly exposed to oxidative stress that may lead to the accumulation of damaged cellular proteins, lipids, nucleic acids, an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650008/ https://www.ncbi.nlm.nih.gov/pubmed/32298788 http://dx.doi.org/10.1016/j.preteyeres.2020.100858 |