The German trial on Aciclovir and Corticosteroids in Herpes-simplex-virus-Encephalitis (GACHE): a multicenter, randomized, double-blind, placebo-controlled trial

INTRODUCTION: Comprehensive treatment of Herpes-simplex-virus-encephalitis (HSVE) remains a major clinical challenge. The current therapy gold standard is aciclovir, a drug that inhibits viral replication. Despite antiviral treatment, mortality remains around 20% and a majority of survivors suffer f...

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Detalles Bibliográficos
Autores principales: Meyding-Lamadé, U., Jacobi, C., Martinez-Torres, F., Lenhard, T., Kress, B., Kieser, M., Klose, C., Einhäupl, K., Bösel, J., Mackert, M-B, Homberg, V., Koennecke, C., Weißheit, G., Claus, D., Kieseier, B., Bardutzky, J., Neumann-Haefelin, T., Lorenz, M. W., Steinmetz, H., Gerloff, C., Schneider, D., Grau, A., Klein, M., Dziewas, R., Bogdahn, U., Jakob, W., Linker, R., Fuchs, K., Sander, A., Luntz, S., Hoppe-Tichy, T., Hanley, D. F., von Kummer, R., Craemer, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650106/
https://www.ncbi.nlm.nih.gov/pubmed/33324892
http://dx.doi.org/10.1186/s42466-019-0031-3

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