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LncRNA MYLK-AS1 facilitates tumor progression and angiogenesis by targeting miR-424-5p/E2F7 axis and activating VEGFR-2 signaling pathway in hepatocellular carcinoma

BACKGROUND: Long non-coding RNAs (lncRNAs) are crucial in the invasion, angiogenesis, progression, and metastasis of hepatocellular carcinoma (HCC). The lncRNA MYLK-AS1 promotes the growth and invasion of HCC through the EGFR/HER2-ERK1/2 signaling pathway. However, the clinical significance of MYLK-...

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Detalles Bibliográficos
Autores principales: Teng, Fei, Zhang, Ju-Xiang, Chang, Qi-Meng, Wu, Xu-Bo, Tang, Wei-Guo, Wang, Jian-Fa, Feng, Jin-Feng, Zhang, Zi-Ping, Hu, Zhi-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650167/
https://www.ncbi.nlm.nih.gov/pubmed/33168027
http://dx.doi.org/10.1186/s13046-020-01739-z