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Zymogen and activated protein C have similar structural architecture

Activated protein C is a trypsin-like protease with anticoagulant and cytoprotective properties that is generated by thrombin from the zymogen precursor protein C in a reaction greatly accelerated by the cofactor thrombomodulin. The molecular details of this activation remain elusive due to the lack...

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Detalles Bibliográficos
Autores principales:	Stojanovski, Bosko M., Pelc, Leslie A., Zuo, Xiaobing, Di Cera, Enrico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650249/ https://www.ncbi.nlm.nih.gov/pubmed/32855236 http://dx.doi.org/10.1074/jbc.RA120.014789

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