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PRMT5 inhibition attenuates cartilage degradation by reducing MAPK and NF-κB signaling

OBJECTIVES: A role for the type II arginine methyltransferase PRMT5 in various human diseases has been identified. In this study, the potential mechanism underlying the involvement of PRMT5 in the pathological process leading to osteoarthritis (OA) was investigated. METHODS: PRMT5 expression in cart...

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Detalles Bibliográficos
Autores principales:	Dong, Yonghui, Wang, Ping, Yang, Yongguang, Huang, Jincheng, Dai, Zhipeng, Zheng, Wendi, Li, Zhen, Yao, Zheng, Zhang, Hongjun, Zheng, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650297/ https://www.ncbi.nlm.nih.gov/pubmed/32887644 http://dx.doi.org/10.1186/s13075-020-02304-x

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