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A non-viral genome editing platform for site-specific insertion of large transgenes

BACKGROUND: The precise, functional and safe insertion of large DNA payloads into host genomes offers versatility in downstream genetic engineering-associated applications, spanning cell and gene therapies, therapeutic protein production, high-throughput cell-based drug screening and reporter cell l...

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Detalles Bibliográficos
Autores principales:	Chaudhari, Namrata, Rickard, Amanda M., Roy, Suki, Dröge, Peter, Makhija, Harshyaa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650303/ https://www.ncbi.nlm.nih.gov/pubmed/32883366 http://dx.doi.org/10.1186/s13287-020-01890-6

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