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EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data

Cell type heterogeneity presents a challenge to the interpretation of epigenome data, compounded by the difficulty in generating reliable single-cell DNA methylomes for large numbers of cells and samples. We present EPISCORE, a computational algorithm that performs virtual microdissection of bulk ti...

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Detalles Bibliográficos
Autores principales:	Teschendorff, Andrew E., Zhu, Tianyu, Breeze, Charles E., Beck, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650528/ https://www.ncbi.nlm.nih.gov/pubmed/32883324 http://dx.doi.org/10.1186/s13059-020-02126-9

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