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Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells
SIMPLE SUMMARY: Human RecQ helicases participate in DNA replication, repair and transcription. Due to important roles in many cellular processes, deregulation of these helicases in cancer could be tumour promoting. We found upregulated RECQL4 expression in highly malignant brain tumours (glioblastom...
Autores principales: | Król, Sylwia K., Kaczmarczyk, Agnieszka, Wojnicki, Kamil, Wojtas, Bartosz, Gielniewski, Bartłomiej, Grajkowska, Wieslawa, Kotulska, Katarzyna, Szczylik, Cezary, Czepko, Ryszard, Banach, Mariusz, Kaspera, Wojciech, Szopa, Wojciech, Marchel, Andrzej, Czernicki, Tomasz, Kaminska, Bozena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650617/ https://www.ncbi.nlm.nih.gov/pubmed/33050631 http://dx.doi.org/10.3390/cancers12102919 |
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