Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase

The anticancer effect of L-asparaginases (L-ASNases) is attributable to their ability to hydrolyze L-asparagine in the bloodstream and cancer cell microenvironment. Rhodospirillum rubrum (RrA) has dual mechanism of action and plays a role in the suppression of telomerase activity. The aim of this wo...

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Detalles Bibliográficos
Autores principales: Plyasova, Anna A., Pokrovskaya, Marina V., Lisitsyna, Olga M., Pokrovsky, Vadim S., Alexandrova, Svetlana S., Hilal, Abdullah, Sokolov, Nikolay N., Zhdanov, Dmitry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650658/
https://www.ncbi.nlm.nih.gov/pubmed/33008089
http://dx.doi.org/10.3390/ph13100286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650658/
https://www.ncbi.nlm.nih.gov/pubmed/33008089
http://dx.doi.org/10.3390/ph13100286

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