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Deep Tumor Penetration of Doxorubicin-Loaded Glycol Chitosan Nanoparticles Using High-Intensity Focused Ultrasound
The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetration of doxorubicin (DOX)-loaded glycol chitosan nan...
Autores principales: | Choi, Yongwhan, Han, Hyounkoo, Jeon, Sangmin, Yoon, Hong Yeol, Kim, Hyuncheol, Kwon, Ick Chan, Kim, Kwangmeyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650702/ https://www.ncbi.nlm.nih.gov/pubmed/33076520 http://dx.doi.org/10.3390/pharmaceutics12100974 |
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