High Levels of miR-7-5p Potentiate Crizotinib-Induced Cytokilling and Autophagic Flux by Targeting RAF1 in NPM-ALK Positive Lymphoma Cells

SIMPLE SUMMARY: Anaplastic lymphoma kinase positive anaplastic large cell lymphomas are a pediatric disease, which still needs treatment improvement. Crizotinib was the first ALK-targeted inhibitor used in clinics, but relapses are now known to occur. Current research efforts indicate that combined...

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Detalles Bibliográficos
Autores principales: Sorrentino, Domenico, Frentzel, Julie, Mitou, Géraldine, Blasco, Rafael B., Torossian, Avédis, Hoareau-Aveilla, Coralie, Pighi, Chiara, Farcé, Manon, Meggetto, Fabienne, Manenti, Stéphane, Espinos, Estelle, Chiarle, Roberto, Giuriato, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650725/
https://www.ncbi.nlm.nih.gov/pubmed/33066037
http://dx.doi.org/10.3390/cancers12102951

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