Cargando…

Dual Targeting of Endothelial and Cancer Cells Potentiates In Vitro Nanobody-Targeted Photodynamic Therapy

SIMPLE SUMMARY: Photodynamic therapy (PDT) eradicates tumors by the local activation of a photosensitizer with appropriate light. Although very promising, its clinical application is limited by the sub-optimal tumor specificity of the photosensitizer. Nanobody-targeted PDT was developed to improve s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mashayekhi, Vida, Xenaki, Katerina T., van Bergen en Henegouwen, Paul M.P., Oliveira, Sabrina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650791/ https://www.ncbi.nlm.nih.gov/pubmed/32977602 http://dx.doi.org/10.3390/cancers12102732

Ejemplares similares

VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells
por: Heukers, Raimond, et al.
Publicado: (2019)

Homogeneous tumor targeting with a single dose of HER2-targeted albumin-binding domain-fused nanobody-drug conjugates results in long-lasting tumor remission in mice
por: Xenaki, Katerina T, et al.
Publicado: (2021)

Antibody or Antibody Fragments: Implications for Molecular Imaging and Targeted Therapy of Solid Tumors
por: Xenaki, Katerina T., et al.
Publicado: (2017)

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic
por: Beltrán Hernández, Irati, et al.
Publicado: (2021)

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging
por: de Bruijn, Henriette S., et al.
Publicado: (2020)

Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells
por: De Groof, Timo W. M., et al.
Publicado: (2019)

The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses
por: Beltrán Hernández, Irati, et al.
Publicado: (2020)

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer
por: van Driel, Pieter B.A.A., et al.
Publicado: (2016)

Vascular targeted photodynamic therapy: A review of the efforts towards molecular targeting of tumor vasculature
por: Mashayekhi, Vida, et al.
Publicado: (2019)

Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session
por: Deken, Marion M., et al.
Publicado: (2020)

Multifaceted Activities of Seven Nanobodies against Complement C4b
por: De la O Becerra, Karla I., et al.
Publicado: (2022)

EGFR-Targeted Nanobody Functionalized Polymeric Micelles Loaded with mTHPC for Selective Photodynamic Therapy
por: Liu, Yanna, et al.
Publicado: (2020)

Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer
por: van Brussel, Aram S. A., et al.
Publicado: (2015)

Specific tumor targeting and activation of Vγ9Vδ2 T cells by bi-specific nanobodies
por: Stam, Anita, et al.
Publicado: (2014)

Development of in vitro-grown spheroids as a 3D tumor model system for solid-state NMR spectroscopy
por: Damman, Reinier, et al.
Publicado: (2020)

Targeted nanobody complex enhanced photodynamic therapy for lung cancer by overcoming tumor microenvironment
por: Zhang, Qing, et al.
Publicado: (2020)

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions
por: van Straten, Demian, et al.
Publicado: (2017)

High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display
por: Salema, Valencio, et al.
Publicado: (2016)

Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody
por: Zeronian, Matthieu R., et al.
Publicado: (2022)

Eps15: a multifunctional adaptor protein regulating intracellular trafficking
por: van Bergen en Henegouwen, Paul MP
Publicado: (2009)

In vitro nanobody discovery for integral membrane protein targets
por: Doshi, Rupak, et al.
Publicado: (2014)

The Impact of Nanobody Density on the Targeting Efficiency of PEGylated Liposomes
por: Mesquita, Bárbara S., et al.
Publicado: (2022)

Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots
por: Katrukha, Eugene A., et al.
Publicado: (2017)

Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
por: Oosterheert, Wout, et al.
Publicado: (2020)

Membrane domain formation—a key factor for targeted intracellular drug delivery
por: Popov-Čeleketić, Dušan, et al.
Publicado: (2014)

Nanobody Conjugates for Targeted Cancer Therapy and Imaging
por: Kang, Wei, et al.
Publicado: (2021)

Dual-Responsive Molecular Probe for Tumor Targeted Imaging and Photodynamic Therapy
por: Meng, Xiaoqing, et al.
Publicado: (2017)

A Nanobody‐on‐Quantum Dot Displacement Assay for Rapid and Sensitive Quantification of the Epidermal Growth Factor Receptor (EGFR)
por: Su, Ruifang, et al.
Publicado: (2022)

Resolving bundled microtubules using anti-tubulin nanobodies
por: Mikhaylova, Marina, et al.
Publicado: (2015)

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors
por: Eichhoff, Anna Marei, et al.
Publicado: (2019)

Targeted photodynamic therapy for breast cancer: the potential of glyconanoparticles
por: Thomas-Moore, Brydie A., et al.
Publicado: (2023)

Nanobody Based Dual Specific CARs
por: De Munter, Stijn, et al.
Publicado: (2018)

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development
por: De Vlaeminck, Yannick, et al.
Publicado: (2020)

Structural Basis of Nanobodies Targeting the Prototype Norovirus
por: Ruoff, Kerstin, et al.
Publicado: (2019)

Development and Characterization of Nanobodies Targeting the Kupffer Cell
por: Zheng, Fang, et al.
Publicado: (2021)

Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer
por: D’Huyvetter, Matthias, et al.
Publicado: (2014)

Nanobody-Based Delivery Systems for Diagnosis and Targeted Tumor Therapy
por: Hu, Yaozhong, et al.
Publicado: (2017)

Targeted Alpha Therapy (TAT) with Single-Domain Antibodies (Nanobodies)
por: Hurley, Kate, et al.
Publicado: (2023)

EGFR-Targeted Photodynamic Therapy
por: Ulfo, Luca, et al.
Publicado: (2022)

Metallobacteriochlorophylls as potential dual agents for photodynamic therapy and chemotherapy
por: Rutkowska-Zbik, Dorota, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_41sfjl28c7ko8vpi36qb4pvkee