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Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing

We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need...

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Detalles Bibliográficos
Autores principales: Springer, Sandra A, Masciotra, Silvina, Johnson, Jeffrey A, Campbell, Sheldon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651562/
https://www.ncbi.nlm.nih.gov/pubmed/33204760
http://dx.doi.org/10.1093/ofid/ofaa478
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author Springer, Sandra A
Masciotra, Silvina
Johnson, Jeffrey A
Campbell, Sheldon
author_facet Springer, Sandra A
Masciotra, Silvina
Johnson, Jeffrey A
Campbell, Sheldon
author_sort Springer, Sandra A
collection PubMed
description We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered in diagnostic guidelines to resolve diagnosis and ensure appropriate ART management.
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spelling pubmed-76515622020-11-16 Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing Springer, Sandra A Masciotra, Silvina Johnson, Jeffrey A Campbell, Sheldon Open Forum Infect Dis Brief Report We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered in diagnostic guidelines to resolve diagnosis and ensure appropriate ART management. Oxford University Press 2020-10-10 /pmc/articles/PMC7651562/ /pubmed/33204760 http://dx.doi.org/10.1093/ofid/ofaa478 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Springer, Sandra A
Masciotra, Silvina
Johnson, Jeffrey A
Campbell, Sheldon
Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title_full Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title_fullStr Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title_full_unstemmed Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title_short Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing
title_sort do i have hiv or not? lack of rna detection and the case for sensitive dna testing
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651562/
https://www.ncbi.nlm.nih.gov/pubmed/33204760
http://dx.doi.org/10.1093/ofid/ofaa478
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