Reliable quantification of (18)F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio

PURPOSE: Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of microglia activation by PET with the translocator protein (TSPO) ligand (18)F-GE-180....

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Detalles Bibliográficos
Autores principales: Buchert, Ralph, Dirks, Meike, Schütze, Christian, Wilke, Florian, Mamach, Martin, Wirries, Ann-Katrin, Pflugrad, Henning, Hamann, Linda, Langer, Laura B.N., Wetzel, Christian, Lukacevic, Mario, Polyak, Andras, Kessler, Mariella, Petrusch, Carlotta, Bengel, Frank M., Geworski, Lilli, Rupprecht, Rainer, Weissenborn, Karin, Ross, Tobias L., Berding, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651670/
https://www.ncbi.nlm.nih.gov/pubmed/32322915
http://dx.doi.org/10.1007/s00259-020-04810-1

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