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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure
The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651836/ https://www.ncbi.nlm.nih.gov/pubmed/33154030 http://dx.doi.org/10.1183/13993003.02384-2020 |
| _version_ | 1783607607449092096 |
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| author | Michalick, Laura Weidenfeld, Sarah Grimmer, Benjamin Fatykhova, Diana Solymosi, Philip Daniel Behrens, Felix Dohmen, Melanie Brack, Markus C. Schulz, Sabrina Thomasch, Elisa Simmons, Szandor Müller-Redetzky, Holger Suttorp, Norbert Kurth, Florian Neudecker, Jens Toennies, Mario Bauer, Torsten T. Eggeling, Stephan Corman, Victor Max Hocke, Andreas C. Witzenrath, Martin Hippenstiel, Stefan Kuebler, Wolfgang M. |
| author_facet | Michalick, Laura Weidenfeld, Sarah Grimmer, Benjamin Fatykhova, Diana Solymosi, Philip Daniel Behrens, Felix Dohmen, Melanie Brack, Markus C. Schulz, Sabrina Thomasch, Elisa Simmons, Szandor Müller-Redetzky, Holger Suttorp, Norbert Kurth, Florian Neudecker, Jens Toennies, Mario Bauer, Torsten T. Eggeling, Stephan Corman, Victor Max Hocke, Andreas C. Witzenrath, Martin Hippenstiel, Stefan Kuebler, Wolfgang M. |
| author_sort | Michalick, Laura |
| collection | PubMed |
| description | The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB |
| format | Online Article Text |
| id | pubmed-7651836 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | European Respiratory Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76518362020-11-16 Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure Michalick, Laura Weidenfeld, Sarah Grimmer, Benjamin Fatykhova, Diana Solymosi, Philip Daniel Behrens, Felix Dohmen, Melanie Brack, Markus C. Schulz, Sabrina Thomasch, Elisa Simmons, Szandor Müller-Redetzky, Holger Suttorp, Norbert Kurth, Florian Neudecker, Jens Toennies, Mario Bauer, Torsten T. Eggeling, Stephan Corman, Victor Max Hocke, Andreas C. Witzenrath, Martin Hippenstiel, Stefan Kuebler, Wolfgang M. Eur Respir J Agora The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB European Respiratory Society 2021-03-11 /pmc/articles/PMC7651836/ /pubmed/33154030 http://dx.doi.org/10.1183/13993003.02384-2020 Text en Copyright ©ERS 2021 http://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. |
| spellingShingle | Agora Michalick, Laura Weidenfeld, Sarah Grimmer, Benjamin Fatykhova, Diana Solymosi, Philip Daniel Behrens, Felix Dohmen, Melanie Brack, Markus C. Schulz, Sabrina Thomasch, Elisa Simmons, Szandor Müller-Redetzky, Holger Suttorp, Norbert Kurth, Florian Neudecker, Jens Toennies, Mario Bauer, Torsten T. Eggeling, Stephan Corman, Victor Max Hocke, Andreas C. Witzenrath, Martin Hippenstiel, Stefan Kuebler, Wolfgang M. Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title | Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title_full | Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title_fullStr | Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title_full_unstemmed | Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title_short | Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure |
| title_sort | plasma mediators in patients with severe covid-19 cause lung endothelial barrier failure |
| topic | Agora |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651836/ https://www.ncbi.nlm.nih.gov/pubmed/33154030 http://dx.doi.org/10.1183/13993003.02384-2020 |
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